Central Nervous System Open Data Portal

An open-access portal tracking research advances and datasets across Alzheimer’s disease, Parkinson’s disease, and ALS. Aggregating scientific findings and open repositories from Alzforum, bioRxiv, OpenNeuro, DANDI, and Agora.

Research Guides (10)Trend Reports (3)Compare Tool Open Datasets Clinical Trials Glossary

Cross-Repository Search & Semantic Discovery

Curated CNS Datasets, Literature & Clinical Trial Index

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The Michael J. Fox FoundationParkinson's & MovementDatabase / Portal

PPMI Flagship Cohort: Neuronal Alpha-Synuclein Disease Integrated Biological Staging System (NSD-ISS) & SAA Dataset

Longitudinal Parkinson’s Progression Markers Initiative (PPMI) dataset spanning >2,000 sporadic PD, prodromal RBD/hyposmia, and LRRK2/GBA1 carriers with CSF alpha-synuclein seed amplification assay (SAA), DAT-SPECT, and 3T MRI.

CSF BiomarkersDAT-SPECT2,100+ Longitudinal SubjectsPPMI Open Research Data Use AgreementFree Registration

Jul 15, 2026Simuni T

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Data Scope & Sources

Data Scope & Synchronized Repositories

This portal tracks and synchronizes open CNS data based on the following criteria: